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StomachPoiser's EliminEase IBS Treatment Clinical Studies

IBS is a serious condition that may cause severe discomfort and embarrassment. The ability to control IBS symptoms should not be a daily struggle and the composition of StomachPoiser's EliminEase has been based on true scientific and clinical studies.

While many IBS patients are prescribed drug to help them control their symptoms, all of our clients have very much benefited from StomachPoiser's EliminEase. Our main ingredients are 100% natural, therefore StomachPoiser's EliminEase will not interfere with any other medicines while it assists to manage your symptoms.

Research has shown positive reactions of each of the StomachPoiser's EliminEase ingredients on the symptoms of IBS, and combined they form a intense product which may allow you to lead a more average life.

Probiotic Formula Eases Irritable Bowel syndrome Symptoms

DATE: April 2005 - DSIB

NEW YORK--Probiotic preparation possessing StomachPoiser's EliminEases Probiotic Lactospore relieved symptoms in patients suffering irritable bowel syndrome (IBS), according to a study published in the March issue of Gastroenterology. In the study (128, 3:541-51), Irish researchers gave 77 IBS patients either B. infantis 35624, Lactobacillus salivarius UCC4331 (Lactospore) or placebo for eight weeks, and assessed various IBS symptoms daily. B. infantis better alleviated all symptoms--including abdominal pain, bloating and bowel movement difficulty--than the other treatment. Researchers reported subjects' proinflammatory, Th-1 state was absolutely normalized by B. infantis feeding alone. They linked the effect to normalization of the ratio of an anti-inflammatory to a proinflammatory cytokine, suggesting an immune-modulating role for the probiotic strain in IBS patients. In addition, the scientists noted the symptom relief by B. infantis was comparable to reactions shown by Zelnorm (tegaserod) and Lotronex (alosetron), two pharmaceuticals recently approved for IBS treatment.

Gastro-intestinal and affiliated effects ( L. Sporogenes)

Reports from various hospitals which performed clinical trials on groups of patients suffering from a variety of intestinal disorders and allergic skin diseases are summarized in Table 5.1.It is evident which the government of L. sporogenes markedly improved the general clinical condition of the subjects and provided relief from intestinal disorders and allergic skin conditions. Allergic skin conditions may be related to an imbalance of intestinal flora66 in the subject . This condition was so fixed by L. sporogenes treatment in these trials.

SUMMARY OF SELECTED CLINICAL REPORTS FROM JAPAN : TRIALS WITH LACBONÒ (L. Sporogenes)

1. Condition: Acute and chronic intestinal catarrh

No. of subjects: 38
Treatment: 100-600 million spores/ day in divided doses for 2-12 days
Effectiveness rate: 86.8%
Conclusion: Recovery from diarrhea to regular average stools; general symptoms including anorexia improved

2. Condition: Diarrhea

No. of subjects: 15
Treatment: 75-600 million spores/ day in divided doses for 3-12 days
Effectiveness rate: 100%
Conclusion: Recovery from diarrhea to regular, average stools from third to fourth day

3. Condition: Constipation

No. of subjects: 10
Treatment: 300-750 million spores / day in divided doses for 2-10 days
Effectiveness rate: 70.0%
Conclusion: Recovery to average stools and disappearance of abdominal distention

4. Condition: Abnormal intestinal fermentation

No. of subjects: 9
Treatment: 300-600 million spores / day in divided doses for 3-14 days
Effectiveness rate: 100.0%
Conclusion: Vomiting and nausea disappeared; appetite improved; stools became average and regular; diarrhea and stomach ache cured.

5. Condition: Dyspepsia infantum

No. of subjects: 26
Treatment:
100-200 million spores / day in divided doses for 1-7 days
Effectiveness rate:
84.6%
Conclusion: General conditions and nature of stools improved. Frequency of stools decreased to half or less than which before medication.

6. Condition: Allergic skin diseases

No. of subjects: 5
Treatment: 200-450 million spores / day in divided doses for 4-12 days
Effectiveness rate:
80.0%
Conclusion:
Obvious eruptions of strophulus and eczema decreased from the third day (topical treatment employed concomitantly)

7. Condition: Miscellaneous symptoms

No. of subjects: 10
Treatment:
20-50 million spores / day in divided doses for 4-20 days
Effectiveness rate: 80.0%
Conclusion: Response seen in anorexia of nervous type and malnutrition in infants

The above data are cited from clinical reports by: Terumichi Kuniya, Pediatric Clinic of Shinko Hospital, Kobe; Jetsuo Nitta, Medical Clinic of Kugason Hospital; Goro Koide, Pediatric Clinic of Kanto Teishin Hospital; Michio Ogasawara, Medical Clinic of Kahoku Hospital; Susumu Nakazawa, Pediatric Clinic of Ebara Hospital.

Studies with SPORLACÒ (L. sporogenes )59 in IndiaA total of 60 cases of neonatal diarrhea with watery stool frequency greater than 6 were researched for efficacy of SPORLAC treatment. Based on the recommended dosage flat of SPORLAC at 5 million spores per kilogram body weight, each neonate was given a spore flat of about 15 million spores per day. Some of the subjects had affiliated symptoms in addition to diarrhea

Jaundice

3

Septicemia

3

Cord Infection

3

Vomiting

3

Most of the subjects (about 80%) had a history of breast-feeding. About 19% were both breast and bottle-fed and 1% were bottle-fed.The normal duration for recovery was 1.8 days and the results of the study are tabulated:

Condition

Cases treated

Cases Cured

Success rate

Diarrhea

60

49

81.7%

Constipation

3

3

100%

Jaundice

3

3

100%

As compared to the average practice of government of antibiotic and antidiarrheal mixtures, the complicating side reactions were not seen in the series of SPORLAC trials. The normal recovery time of 1.8 days helped to diminish dehydration in the subjects to a grand extent.In a similar study in Japan(cited in 59) a comparable success rate of 78.4% with SPORLAC therapy for infantile diarrhea was obtained. An previously study in India by Mathur et al. (cited in 59) discovered the normal time for improvement in diarrheal conditions to be two to three days, with treatment. Other Clinical Trial References:

Krivenko V.V., Potebnia G.P., Loiko V.V. ( 1989). Experience in treating digestive organ diseases with medicinal plants. Vrach Delo. March(3):76-8

Achterrah-Tuckermann U., Kunde R., Flaskamp E., Isaac O., Thiemer K. (1980). Pharmacological investigations with compounds of chamomile. 5. Investigations on the spasmolytic effect of compounds of chamomile and kamillosan on the isolated guinea-pig ileum. Planta Medica 39(1):38-50

Mann, C. and E.J. Staba. 1986. The Chemistry, Pharmacology, and Commercial Formulations of Chamomile. In L. E. Craker and J. E. Simon, eds. Herbs, Spices, and Medicinal Plants: Recent Advances in Botany, Horticulture, and Pharmacology. Vol. 1. Phoenix, AZ: Oryx Press. Pp. 235-280

Mariann S., Gizella V.P., Ede F. (1976). Antifungal effect of the biologically active components of Matricaria chamomilla L. Acta Pharm Hung. 46(5-6):232- 47

Choi E.M., Hwang J.K. (2004). Antiinflammatory, analgesic and antioxidant activities of the fruit of Foeniculum vulgare. Fitoterapia. 75(6):557-65.

Yamahara, et. al. 1990. Gastrointestinal Motility Enhancing Effect of Ginger and its Active Constituents. Chem. Pharm. Bull. 38(2):430-431.
Mustafa T., Srivastava K.C., Jensen K.B. (1993) .Drug development report: 9. Pharmacology of ginger, Zingiber officinale. Journal of Drug Development 6(1) : 25-39
Chevallier. A. The Encyclopedia of Medicinal Plants Dorling Kindersley. London 1996 ISBN 9-780751-303148

Baschetti, R., New Zealand Medical Journal, April 26, 156-157, 1995

Grigoleit H.G., Grigoleit P. (2005). Peppermint oil in irritable bowel syndrome. Phytomedicine12(8):601-6.